APPLICATION OF FUNCTIONAL NEAR-INFRARED SPECTROSCOPY IN NEUROLOGICAL DISEASES: EPILEPSY, STROKE AND PARKINSON

Author:

HU XINHUA1,XIAO GANG2,ZHU KEXIN3,HU SHUYI3,CHEN JIU4,YU YUN5

Affiliation:

1. Department of Neurosurgery, the Affiliated Brain Hospital of Nanjing Medical University, Nanjing Medical University, Institute of Brain Functional Imaging, Nanjing Medical University, Nanjing, Jiangsu, 210029, P. R. China

2. The Key Laboratory of Metabolism and Molecular Medicine of the Ministry of Education, Department of Biochemistry and Molecular Biology of School of Basic Medical Sciences and Department of Endocrinology, Fudan University, Shanghai, 200032, P. R. China

3. The First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, Jiangsu, 210029, P. R. China

4. Institute of Brain Functional Imaging, Nanjing Medical University, Nanjing, Jiangsu, 210029, P. R. China

5. Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Institute of Brain Functional Imaging, Nanjing Medical University, Nanjing, Jiangsu, 210029, P. R. China

Abstract

The functional near-infrared spectroscopy (fNIRS) technology is an optical imaging technology that applies near-infrared light to measure the oxygenated and deoxygenated hemoglobin concentration alteration in cortical brain structures. It has the ability to directly measure changes in the blood oxygen level of the high temporal resolution associated with neural activation. Thus, it has been utilized in different neurological diseases, such as epilepsy, stroke, and Parkinson. The work of this paper will focus on the application of the fNIRS in the three neurological diseases and the principle of fNIRS. Moreover, the difficulties and challenges that the technology is currently experiencing have been discussed.

Funder

the Jiangsu Provincial University Philosophy and Social Science Research Fund Project

Publisher

World Scientific Pub Co Pte Lt

Subject

Biomedical Engineering

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