COMPARISON OF THE EFFECTS OF WALKING AND BENCH-STEP EXERCISE ON OSTEOCALCIN AND CTX-1 IN POST-MENOPAUSAL WOMEN WITH OSTEOPENIA

Author:

Haryono Ignatio Rika1,Tulaar Angela2,Sudoyo Herawati3,Purba Ambrosius4,Abdullah Murdani5,Jusman Sri Widia6,Lubis Andri M. T.7,Ibrahim Ilyas Ermita I.8

Affiliation:

1. Department of Physiology, Faculty of Medicine, Atma Jaya Catholic University of Indonesia, Jakarta 10440, Indonesia

2. Department of Physic and Rehabilitation, Faculty of Medicine, Universitas Indonesia — Dr Cipto Mangunkusumo General Hospital, Jakarta 10430, Indonesia

3. Eijkman Institute for Molecular Biology, Jakarta 10430, Indonesia

4. Department of Physiology, Faculty of Medicine, Padjadjaran University, Bandung 40161, Indonesia

5. Department of Internal Medicine, Division of Gastroenterology, Faculty of Medicine, Universitas Indonesia — Dr Cipto Mangunkusumo General Hospital, Jakarta 10430, Indonesia

6. Department of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta 10430, Indonesia

7. Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Indonesia — Dr Cipto Mangunkusumo General Hospital, Jakarta 10430, Indonesia

8. Department of Medical Physiology, Faculty of Medicine, Universitas Indonesia, Jakarta 10430, Indonesia

Abstract

Purpose: Bench-step exercise produces biomechanical movements beneficial to improve bone remodeling. However, no studies have confirmed the effects of bench-step exercise (BE) on bone formation and resorption. The goal of this study is to compare the effects of bench-step and walking exercise (WE) on changes in osteocalcin and CTX-1 levels. Methods: Fifty-nine sedentary post-menopausal women with osteopenia (T-score between [Formula: see text]1 and [Formula: see text]2.5) were randomly divided into two groups: WE group ([Formula: see text]) and BE group ([Formula: see text]). Subjects performed 12 weeks of exercise. The osteocalcin and CTX-1 levels were analyzed using enzyme-linked immunosorbent assay. Independent [Formula: see text]-test or Wilcoxon test was used to analyze the osteocalcin and CTX-1 levels. The difference in changes in the osteocalcin and CTX-1 between the groups before and after was analyzed using Mann–Whitney test. Results: The results showed a significant increase in the osteocalcin and CTX-1 levels in both groups ([Formula: see text]). The increased levels of osteocalcin between groups were not statistically different ([Formula: see text]). The increase in CTX-1 resulting from BE was lower than that from WE ([Formula: see text]). Conclusion: This study indicates that BE may inhibit resorption stronger than WE.

Funder

Simlitabmas, Kementerian Pendidikan Nasional

Atma Jaya Catholic University

Publisher

World Scientific Pub Co Pte Lt

Subject

Orthopedics and Sports Medicine

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