MIXED VACCINATION STRATEGY IN SIRS EPIDEMIC MODEL WITH SEASONAL VARIABILITY ON INFECTION

Author:

GAO SHUJING12,OUYANG HONGSHUI1,NIETO JUAN J.3

Affiliation:

1. Key Laboratory of Jiangxi Province for Numerical Simulation and Emulation Techniques, Gannan Normal University, Ganzhou 341000, P. R. China

2. National Institute of Parasitic Disease, Chinese Center of Disease Control and Prevention, China

3. Departamento de Análisis Matemático, Facultad de Matemáticas, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain

Abstract

In many diseases seasonal fluctuations are observed. SIRS epidemic model with seasonal varying contact rate and mixed vaccination strategy (including first vaccination and pulse vaccination strategy) is investigated. The effects of the variation of dependent on the season of the contact rate and the vaccination strategy to eradicate infectious diseases are studied and discussed. A threshold for a disease to be extinct or endemic is established. The existence and global asymptotic stability of disease-free periodic solution and the permanence of the disease are illustrated. Finally, our theoretical results are confirmed by numerical simulations.

Publisher

World Scientific Pub Co Pte Lt

Subject

Applied Mathematics,Modelling and Simulation

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