NUMERICAL SIMULATION OF TRANSIENT BLOOD FLOW THROUGH THE LEFT CORONARY ARTERY WITH VARYING DEGREES OF BIFURCATION ANGLES

Author:

ZHANG BO1,JIN YILUN2,WANG XIAORAN2,ZENG TAISHENG3ORCID,WANG LIANSHENG2

Affiliation:

1. Department of Ultrasound in Medicine, Shanghai East Hospital, Tongji University School of Medicine, No. 150 Jimo Rd., Shanghai 200120, P. R. China

2. Department of Computer Science, School of Information Science and Engineering, Xiamen University, Fujian, Xiamen 361005, P. R. China

3. Faculty of Mathematics and Computer Science, Quanzhou Normal University, Fujian, Quanzhou 362000, P. R. China

Abstract

Atherosclerosis is a cardiovascular condition that can occur in any part of the vascular system. Especially, it can exist in bifurcated arteries such as the left and right coronary arteries, abdominal aortic bifurcation or carotid artery bifurcation. In our study, we examine the left coronary artery as an exemplification using wall shear stress (WSS) and wall pressure gradient (WPG). Then, we attempt to find the relationship between bifurcated arterial geometry and hemodynamics. Computational fluid dynamics (CFD) is a common technique applied to characterize blood flow accurately and assist us to gain an insight of atherosclerosis. In this paper, we used CFD as the computational hemodynamics analysis technique to examine flow through the left coronary artery that has variable angular bifurcation. Our results demonstrated that the region of low WSS area and magnitudes of maximum WPG increases with the angles of bifurcation. Such hemodynamic condition resulting from the large bifurcation angles has an effect on atherogenesis and is worthy of investigation for better understanding of atherosclerosis.

Funder

the Academic Leaders Training Program of Pudong Health Bureau of Shanghai

the National Natural Science Foundation of China

Publisher

World Scientific Pub Co Pte Lt

Subject

Biomedical Engineering

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