A REACTION–DIFFUSION MODEL FOR THE CONTROL OF CHOLERA EPIDEMIC

Abstract

Understanding the spatio-temporal dynamics of cholera outbreaks may help in devising more effective control procedures. In this paper, we have considered a reaction–diffusion system for biological control of cholera epidemic. Firstly, we have focused on temporal evolution of cholera in a region and its control using lytic bacteriophage in the aquatic reservoirs. Then, we have explored the effect of spatial dispersion of populations on the disease dynamics. We have observed the onset of sustained oscillations via Hopf-bifurcation for the endemic state of temporal system. This onset of fluctuations in populations depends upon the phage adsorption rate. But in the spatially extended setting, all the populations stabilize i.e., the spatio-temporal distribution of all the populations becomes uniform. Some numerical computations have been done to verify analytical results.