Fabrication Techniques for Production of Thermoplastic-Based Microfluidics Devices

Abstract

Microfluidics is a multidisciplinary technology which enables the face-lift crossing a wide range of applications such as life science research, point-of-care diagnostics and personal medicine. Polymer materials, especially thermoplastics, are dominating this emerging market due to the low material cost and the ease of mass production. This paper reviews the major fabrication technologies for making polymer, especially thermoplastic microfluidic chips, such as micro tooling, injection molding, bonding and surface treatment. The paper also summarizes the key challenges in fulfilling the needs of next generation microfluidic products.