AUTMINER: A SYSTEM FOR EXTRACTING ASD-RELATED GENES USING TEXT MINING-Reference-Cited by-同舟云学术

AUTMINER: A SYSTEM FOR EXTRACTING ASD-RELATED GENES USING TEXT MINING

Published:2011-03 Issue:01 Volume:19 Page:113-125
ISSN:0218-3390
Container-title:Journal of Biological Systems
language:en
Short-container-title:J. Biol. Syst.

Author:

GONG LEJUN¹²,SUN XIAO¹,JIANG DONGKE¹,GONG SHENGTAO¹

Affiliation:

1. State Key Laboratory of Bioelectronics, Department of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, P. R. China

2. Faculty of Computer Engineering, Huaiyin Institute of Technology, Huaian 223003, P. R. China

Abstract

Autism spectrum disorders (ASD) represent a group of developmental disorders with strong genetic underpinnings. To explore the genetic complexity of ASD, we developed AutMiner (), a public web-portal for the collection of genes linked to ASD, and the implementation of an autism-centre network. AutMiner extracts candidate genes associated with ASD using text mining from 9276 abstracts. Compared to other recent systems, gene entries are richer to provide a reference for clinical geneticists. AutMiner also constructs ASD-related network consisting of autism-gene network and gene-gene network. To the best of our knowledge, this is the first web example of ASD-related network. The major focus of AutMiner is to offer a valuable reference tool for clinical geneticists in establishing and implementing effective genetic screening programmes for those patients with ASD.

Publisher

World Scientific Pub Co Pte Lt

Subject

Applied Mathematics,Agricultural and Biological Sciences (miscellaneous),Ecology,Applied Mathematics,Agricultural and Biological Sciences (miscellaneous),Ecology

Link

https://www.worldscientific.com/doi/pdf/10.1142/S0218339011003828

Reference28 articles.

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2. Strong Association of De Novo Copy Number Mutations with Autism

3. Autism as a strongly genetic disorder: evidence from a British twin study

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