STUDY OF TRACE ELEMENTS IN CELLS USING SPM, SR-XRM AND PIXE

Author:

HUANG JUN1,YAO HUIYING1,WU XIANKANG2,LU RONGRONG2,GU YINGMEI2,ZHU JIEQING2,ZHANG JINGXIA3,HUANG PING3,WU BENJIE3,XIAO YANAN4,CHAO ZHIYU4

Affiliation:

1. Dept. of Nuclear Science, Fudan University, Shanghai, China

2. Shanghai Institute of Nuclear Research, Academia Sinica, China

3. Beijing Medical University, Beijing, China

4. BEPC National Laboratory, Beijing, China

Abstract

Trace elements play important roles in cells. Nuclear techniques as traditional PIXE, SPM and SR-XRM provide solid tools for quantitative element analysis. The article presents element-distribution maps of endometrium, nerve cell and relative quantity tables. Advantages of PIXE, SPM and SR-XRM techniques, especially in application to cell biology, are discussed. PIXE has a large beam and is convenient in measuring a large quantity of samples. SPM gives element-distribution maps owing to its high resolution. SR-XRM tells quantity of elements by its good sensitivity and nondestructive irradiation. The combination of PIXE, SPM and SR-XRM demonstrates that Zn is a component of cell membrane and is proved to be a complementary way which will open vast vistas for cell analysis.

Publisher

World Scientific Pub Co Pte Lt

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Quantitative analysis of very small quantities of cultured cells;International Journal of PIXE;2015-01

2. Analysis by absorption and scattering of radiation;Journal of Radioanalytical and Nuclear Chemistry;1998-11

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