RESEARCH ON THE CORRELATION OF TRACE ELEMENTS IN WHOLE BLOOD WITH ACUTE LEUKEMIA BY PIXE-Reference-Cited by-同舟云学术

RESEARCH ON THE CORRELATION OF TRACE ELEMENTS IN WHOLE BLOOD WITH ACUTE LEUKEMIA BY PIXE

Published:1992-01 Issue:04 Volume:02 Page:569-573
ISSN:0129-0835
Container-title:International Journal of PIXE
language:en
Short-container-title:Int. J. PIXE

Author:

Yin Sha¹,Pingsheng Liu¹,Peiqun Zhang¹,Guodong Liu²,Han Lin²,Bing Yang²,Linsheng Qian³

Affiliation:

1. Institute of High Energy Physics, Academia Sinica, P.O. Box 2732, Beijing 100080, P.R. of China

2. Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjing, P.R. of China

3. Institute of Hematology, Chinese Academy of Medical Sciences, Tianjing, P.R. of China

Abstract

The contents of multi-elements in whole blood from 115 patients with 7 different types of acute leukemia and 38 well matched healthy controls have been determined by means of proton induced X-ray emission (PIXE). The number of available analyzed elements was as many as 11, mainly due to the use of a 100 um thick Cr funny foi1 as an absorber. The contents of elements Cu, Ca, S, P, Si and the ratio of Cu to Zn (Cu/Zn) were higher and those of elements Zn, K, Fe, Al and Rb were lower with high significant differences (P<0. 01) in acute leukemia patients than in norma1 controls. The results indicate that the contents of Cu, Zn, and the ratio Cu/Zn are useful indices of disease activity. The elements of Al and Rb may play important roles in acute leukemia etiology,

Publisher

World Scientific Pub Co Pte Lt

Link

https://www.worldscientific.com/doi/pdf/10.1142/S0129083592000610

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