Maleimide-functionalized BODIPY dyes: Synthesis, structural determination and conjugation with carborane thiols

Abstract

A series of new BODIPY conjugates containing maleimide or carborane-succinimide-triazole functional groups were prepared from synthetically available azido-substituted BODIPYs. The structure of new synthesized compounds was characterized by UV-vis, IR, NMR and mass spectrometry. The crystal structures of BODIPY-maleimide conjugates were determined by single crystal X-ray diffraction study. The carborane-containing BODIPYs can be promising agents for photodynamic and boron neutron capture therapy.