Asymmetric zinc phthalocyanines substituted with a single carboxyl and triethyleneoxysulfonyl groups: synthesis, characterization and validation for photodynamic therapy

Author:

Tekdaş Duygu Aydın1,Gürek Ayşe G.1,Ahsen Vefa1

Affiliation:

1. Gebze Institute of Technology, Department of Chemistry, P.O. Box 141, Gebze, Kocaeli 41400, Turkey

Abstract

This work describes modular pathway towards the synthesis of new specific unsymmetrically (AB3) zinc phthalocyanines that contains three polyoxy ethylene and monocarboxylic acid groups as photosensitizers. Their photophysical and photochemical properties are studied. General trends are described for quantum yields of fluorescence, photodegradation and singlet oxygen quantum yields of these compounds. Therefore, these novel phthalocyanines could potentially be good photosensitizers for photodynamic therapy.

Publisher

World Scientific Pub Co Pte Lt

Subject

General Chemistry

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