REDUCED BIO-BASIS FUNCTION NEURAL NETWORKS FOR PROTEASE CLEAVAGE SITE PREDICTION-Reference-Cited by-同舟云学术

REDUCED BIO-BASIS FUNCTION NEURAL NETWORKS FOR PROTEASE CLEAVAGE SITE PREDICTION

Published:2004-09 Issue:03 Volume:02 Page:511-531
ISSN:0219-7200
Container-title:Journal of Bioinformatics and Computational Biology
language:en
Short-container-title:J. Bioinform. Comput. Biol.

Author:

YANG ZHENG RONG¹,BERRY EMILY A.¹

Affiliation:

1. Department of Computer Science, Exeter University, Exeter EX4 4QF, UK

Abstract

This paper presents a new neural learning algorithm for protease cleavage site prediction. The basic idea is to replace the radial basis function used in radial basis function neural networks by a so-called bio-basis function using amino acid similarity matrices. Mutual information is used to select bio-bases and a corresponding selection algorithm is developed. The algorithm has been applied to the prediction of HIV and Hepatitis C virus protease cleavage sites in proteins with success.

Publisher

World Scientific Pub Co Pte Lt

Subject

Computer Science Applications,Molecular Biology,Biochemistry

Link

https://www.worldscientific.com/doi/pdf/10.1142/S0219720004000715

Reference75 articles.

1. T. Alber, Mobility and Function in Proteins and Nucleic Acids, Ciba Foundation Symposium 93, ed. F. M. Richards (1982) pp. 4–24.

2. An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection.

3. Predicting the conformation of proteins from sequences. Progress and future progress

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The self-regulating on cohesion properties of calcium phosphate/ calcium sulfate bone cement improved by citric acid/sodium alginate;Colloids and Surfaces B: Biointerfaces;2023-11

2. Using Pseudo Amino Acid Composition to Predict Protease Families by Incorporating a Series of Protein Biological Features;Protein & Peptide Letters;2011-06-01

3. Neural Networks;Methods in Molecular Biology;2009-10-30

4. Predicting proteolytic sites in extracellular proteins: only halfway there;Bioinformatics;2008-03-04

5. Peptide Bioinformatics- Peptide Classification Using Peptide Machines;Methods in Molecular Biology™;2008