Recurrent Implantation Failure Associated to Morular Endometrial Metaplasia, and Hysteroscopic Management-Reference-Cited by-同舟云学术

Recurrent Implantation Failure Associated to Morular Endometrial Metaplasia, and Hysteroscopic Management

Published:2023-05-20 Issue:02 Volume:05 Page:101-104
ISSN:2661-3182
Container-title:Fertility & Reproduction
language:en
Short-container-title:FandR

Author:

Reyftmann Lionel¹²^ORCID,Vermey Belinda¹,Knight Bryan³

Affiliation:

1. Genea Elements Illawarra, Wollongong, NSW, Australia

2. Graduate Medicine, University of Wollongong, Wollongong, NSW, Australia

3. Department of Anatomical Pathology, Southern IML Pathology, SONIC Laboratories, Wollongong, NSW, Australia

Abstract

We report the first documented case of recurrent implantation failure (RIF) related to morular endometrial metaplasia. A 35-year-old woman with RIF was diagnosed with endometrial morular metaplasia and treated with hysteroscopically guided excision allowing a live birth after the transfer of a single IVF embryo. Subtle endometrial changes, such as endometritis or bone metaplasia, have long been known to impair the success of embryo implantation, but this observation reports the first case of squamous morular endometrial metaplasia to be diagnosed and treated conservatively before a successful single embryo transfer.

Publisher

World Scientific Pub Co Pte Ltd

Subject

General Medicine

Link

https://www.worldscientific.com/doi/pdf/10.1142/S2661318223500123

Reference9 articles.

1. Don’t be STUMPed: description and management of uncommon pathologies encountered on specimens from benign gynecologic surgery

2. An Immunohistochemical Study of Morules in Endometrioid Lesions of the Female Genital Tract: CD10 Is a Characteristic Marker of Morular Metaplasia

3. Hysteroscopy in recurrent in-vitro fertilisation failure (TROPHY): a multicentre, randomised controlled trial

4. Benign and Premalignant Lesions of the Endometrium