DIETARY SUPPLEMENTATION OF GANODERMA LUCIDUM POWDER ENHANCES SURVIVAL AND IMMUNOCOMPETENCE OF WEANING PIGS

Author:

Lee Kuo-Hua1,Nien Pi-Chu2,Chen Tsung-Chi3,Yeh Chia-Chou45,Chen Jih-Yih6,Lin Wen-Hung7,Lee Tzu-Tai8,Jea Yu-Shine1,Chi Chau-Hwa9

Affiliation:

1. Hsin-Chu Branch Station, COA-TRI, Hsin-Chu, Taiwan

2. Changhua Animal Propagation Station, COA-LRI, Beidou, Changhua, Taiwan

3. Department of Biotechnology, Asia University, Taichung, Taiwan

4. School of Medicine, Department of Medicine, Tzu Chi University, Hualien, Taiwan

5. Department of Chinese Medicine, Buddhist Dalin Tzu Chi General Hospital, Chia-Yi, Taiwan

6. Ilan Branch Station, COA-TRI, Ilan, Taiwan

7. Department of Bioinformatics, Chung Hua University, Hsinchu, Taiwan

8. Department of Animal Science, National Chung-Hsing University, Taichung, Taiwan

9. Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan

Abstract

The study was conducted to investigate the effects of Ganoderma lucidum (GL) on growth performance, survival rates, and immunocompetence of the weaning pigs. A total of 45, 28-day-old Landrace weaning pigs were randomly divided into three groups of 15 pigs each. A corn–soybean meal-based control diet was formulated and the experimental diets included 0.3% and 0.6% GL powder. The groups were treated for 38 days. Pigs which fed both concentration of GL powder had significantly higher ([Formula: see text]) survival rates than the control group. Besides, pigs which fed 0.3% and 0.6% GL powder had increased lymphocyte proliferation indexes ([Formula: see text]) and the titer of neutralizing antibody against hog cholera (HC) ([Formula: see text]) on day 66 compared with pigs which fed control diet. No differences were found between treatments regarding the average daily gain (ADG), gain:feed (G:F) ratio and diarrhea score. Supplementation of GL powder showed no effects on aspartate aminotransferase (AST) and blood urea nitrogen (BUN), which suggested that GL treatment has no immediate harm on liver or kidney. Based on these results, GL could be suggested as a potential feed additive of weaning pig diets to increase survival rate and immunocompetence.

Publisher

World Scientific Pub Co Pte Lt

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