NON-HARMONIC DNA BENDING ELASTICITY IS REVEALED BY STATISTICS OF DNA MINICIRCLE SHAPES-Reference-Cited by-同舟云学术

NON-HARMONIC DNA BENDING ELASTICITY IS REVEALED BY STATISTICS OF DNA MINICIRCLE SHAPES

Published:2010-11-10 Issue:28 Volume:24 Page:5475-5485
ISSN:0217-9792
Container-title:International Journal of Modern Physics B
language:en
Short-container-title:Int. J. Mod. Phys. B

Author:

CHEN HU¹,FU HONGXIA¹,ZHOU ZHEN²,YAN JIE¹²

Affiliation:

1. Mechanobiology Institute, National University of Singapore, 5A Engineering Drive 1, Singapore 117543, Singapore

2. Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542, Singapore

Abstract

Unusual DNA elasticity has been observed in a few recent experiments for DNA under tight bending conditions. Here we present new experimental evidence demonstrating unusual DNA bending elasticity by analyzing the atomic force microscope (AFM) images of DNA minicircles of sizes 189 and 378 base-pairs that are relaxed on 2D surface. The DNA shape distributions are found in disagreement with the canonical 50 nm persistence length based worm-like chain (WLC) model. Instead, they are found in agreement with the recently proposed flexible defect excitation model and linear subelastic chain (LSEC) model.

Publisher

World Scientific Pub Co Pte Lt

Subject

Condensed Matter Physics,Statistical and Nonlinear Physics

Link

https://www.worldscientific.com/doi/pdf/10.1142/S0217979210056682

Reference31 articles.

1. Remeasuring the Double Helix

2. DNA overwinds when stretched

3. Spontaneous Sharp Bending of Double-Stranded DNA

4. Biocompatible Force Sensor with Optical Readout and Dimensions of 6 nm3

5. High flexibility of DNA on short length scales probed by atomic force microscopy

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