A NOTE ON THE ANALYSIS OF A HETEROGENEOUS ROD-LIKE CHAIN IN DNA MODELING

Author:

DING YAN1,LI TIEJUN1

Affiliation:

1. LMAM and School of Mathematical Sciences, Peking University, Beijing 100871, China

Abstract

Two different results concerning the elastic behavior of the heterogeneous worm-like chain (WLC) [D. Bensimon et al., Europhys. Lett.42, 97 (1998)] and rod-like chain (RLC) [P. Nelson, Phys. Rev. Lett.80, 5810 (1998)] are compared. We argue that the RLC is a more suitable model for double-stranded (ds-) DNA. As the hetero-RLC is the basic model for studying sequence-dependent ds-DNA, a rigorous path integral analysis for the effective bending persistence length is performed in the weak disorder limit. The novelty of the paper is in analyzing a path integral on the Lie group SO(3) with random forcing, which supplies a rigorous basis for the analysis of RLC type models.

Publisher

World Scientific Pub Co Pte Lt

Subject

Condensed Matter Physics,Statistical and Nonlinear Physics

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