TRANSITION METALS EFFECT ON THE STRUCTURE OF PYRAZINAMIDE COMPLEXES

Author:

SIMON V.1,JURCA T.2,SIMON S.1

Affiliation:

1. Faculty of Physics, Babes-Bolyai University, 3400 Cluj-Napoca, Romania

2. Faculty of Medicine and Pharmacy, University of Oradea, 3700 Oradea, Romania

Abstract

Pyrazinamide (PZA) is among the first-line drugs for the treatment of tuberculosis, which seems to reappear as a frequent disease. In this study we investigate the structural changes induced in these samples as evidenced by thermal behaviour and electron spin resonance of new transition metal complexes of PZA. We is search for a correlation between structure and thermal transformations described as multi-step processes consisting in crystalline phase transition, decomposition, melting and thermo-oxidation.

Publisher

World Scientific Pub Co Pte Lt

Subject

Condensed Matter Physics,Statistical and Nonlinear Physics

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Spectral, thermal studies and biological activity of pyrazinamide complexes;Heliyon;2019-11

2. Metal Complexes of Pharmaceutical Substances;Spectroscopic Analyses - Developments and Applications;2017-12-06

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