CORTICAL EXCITABILITY AS A POTENTIAL CLINICAL MARKER OF EPILEPSY: A REVIEW OF THE CLINICAL APPLICATION OF TRANSCRANIAL MAGNETIC STIMULATION-Reference-Cited by-同舟云学术

CORTICAL EXCITABILITY AS A POTENTIAL CLINICAL MARKER OF EPILEPSY: A REVIEW OF THE CLINICAL APPLICATION OF TRANSCRANIAL MAGNETIC STIMULATION

Published:2014-01-29 Issue:02 Volume:24 Page:1430001
ISSN:0129-0657
Container-title:International Journal of Neural Systems
language:en
Short-container-title:Int. J. Neur. Syst.

Author:

BAUER PRISCA R.¹,KALITZIN STILIYAN¹,ZIJLMANS MAEIKE¹²,SANDER JOSEMIR W.¹³⁴,VISSER GERHARD H.¹

Affiliation:

1. SEIN - Epilepsy Institute in the Netherlands Foundation, Heemstede, The Netherlands, P.O. Box 540, 2130 AM Hoofddorp, The Netherlands

2. Department of Neurology, Brain Center Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands

3. NIHR University College London Hospitals Biomedical Research Centre, UCL Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom

4. Epilepsy Society, Chalfont St Peter, SL9 0RJ, United Kingdom

Abstract

Transcranial magnetic stimulation (TMS) can be used for safe, noninvasive probing of cortical excitability (CE). We review 50 studies that measured CE in people with epilepsy. Most showed cortical hyperexcitability, which can be corrected with anti-epileptic drug treatment. Several studies showed that decrease of CE after epilepsy surgery is predictive of good seizure outcome. CE is a potential biomarker for epilepsy. Clinical application may include outcome prediction of drug treatment and epilepsy surgery.

Publisher

World Scientific Pub Co Pte Lt

Subject

Computer Networks and Communications,General Medicine

Link

https://www.worldscientific.com/doi/pdf/10.1142/S0129065714300010

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