Towards a Computed-Aided Diagnosis System in Colonoscopy: Automatic Polyp Segmentation Using Convolution Neural Networks

Author:

Brandao Patrick1ORCID,Zisimopoulos Odysseas1,Mazomenos Evangelos1,Ciuti Gastone2,Bernal Jorge3,Visentini-Scarzanella Marco4,Menciassi Arianna2,Dario Paolo2,Koulaouzidis Anastasios5,Arezzo Alberto6,Hawkes David J1,Stoyanov Danail1

Affiliation:

1. Centre for Medical Image Computing, University College London, London, UK

2. The BioRobotics Institute, Scuola Superiore Sant’Anna, Pisa, Italy

3. Department of Computer Science Universitat Autnoma de Barcelona, Barcelona, Spain

4. Multimedia Laboratory, Corporate Research and Development Center, Toshiba Kawasaki, Japan

5. UEndoscopy Unit, The Royal Infirmary of Edinburgh, Edinburgh, UK

6. Department of Surgical Sciences, University of Turin, Turin, Italy

Abstract

Early diagnosis is essential for the successful treatment of bowel cancers including colorectal cancer (CRC), and capsule endoscopic imaging with robotic actuation can be a valuable diagnostic tool when combined with automated image analysis. We present a deep learning rooted detection and segmentation framework for recognizing lesions in colonoscopy and capsule endoscopy images. We restructure established convolution architectures, such as VGG and ResNets, by converting them into fully-connected convolution networks (FCNs), fine-tune them and study their capabilities for polyp segmentation and detection. We additionally use shape-from-shading (SfS) to recover depth and provide a richer representation of the tissue’s structure in colonoscopy images. Depth is incorporated into our network models as an additional input channel to the RGB information and we demonstrate that the resulting network yields improved performance. Our networks are tested on publicly available datasets and the most accurate segmentation model achieved a mean segmentation interception over union (IU) of 47.78% and 56.95% on the ETIS-Larib and CVC-Colon datasets, respectively. For polyp detection, the top performing models we propose surpass the current state-of-the-art with detection recalls superior to 90% for all datasets tested. To our knowledge, we present the first work to use FCNs for polyp segmentation in addition to proposing a novel combination of SfS and RGB that boosts performance.

Funder

H2020 European Research Council

Publisher

World Scientific Pub Co Pte Lt

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