Prevalence of Class 1 Integron among Multidrug-Resistant Acinetobacter baumannii in Tabriz, Northwest of Iran

Author:

PEYMANI AMIR,FARAJNIA SAFAR,NAHAEI MOHAMMAD REZA,SOHRABI NASROLLAH,ABBASI LALEH,ANSARIN KHALIL,AZHARI FATEMEH

Abstract

Integrons are associated with a variety of gene cassettes, which confer resistance to multiple classes of antibacterial drugs. In this study we tested the frequency of class 1 and 2 integrons among multidrug-resistant Acinetobacter baumannii (MDRAB) clinical isolates. One hundred clinical isolates of A. baumannii were screened for carriage of class 1 and 2 integrons by PCR method. Results showed that seventy four (92.5%) of 80 MDRAB carried class 1 integron. Integron-positive isolates were statistically more resistant to aminoglycoside, quinolone and beta-lactam compounds except for cefepime. This is the first report of class 1 integrons in MDRAB isolates in northwest Iran.

Publisher

Polish Society of Microbiologists

Subject

Microbiology (medical),Applied Microbiology and Biotechnology,General Medicine,Microbiology

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