To the 100th anniversary of the birth of academician V.A. Nasonova. Infections and rheumatic diseases: from the past to the future

Author:

Belov B. S.1ORCID,Nasonov E. L.2ORCID

Affiliation:

1. V.A. Nasonova Research Institute of Rheumatology

2. V.A. Nasonova Research Institute of Rheumatology; I.M. Sechenov First Moscow State Medical University of the Ministry of Health Care of Russian Federation (Sechenov University)

Abstract

In rheumatology, the problem of infectious pathology is quite acute. This is primarily due to the participation of various infectious agents in the development of immuno-inflammatory rheumatic diseases (IIRD), in which microorganisms play a trigger role, triggering the immunopathological mechanisms of inflammation. Vivid examples of such diseases are acute rheumatic fever and reactive arthritis. The infectious etiology of Lyme disease has been proven. An equally difficult task is the fight against comorbid infection (CI), which often complicates the course of many IIRD due to a violation of the immune status caused by both the background disease and the use of immunosuppressive drugs. The predominance of respiratory tract lesions in the structure of CI in patients with IIRD makes it necessary to use influenza and pneumococcal vaccines in them, since the risk of deaths from these infections among these patients is quite high. During the development of the COVID-19 pandemic, which has become a challenge to all mankind, a large number of new fundamental and medical problems have been revealed concerning the relationship between viral infection and many widespread chronic non-communicable diseases, among which IIRDs occupy an important position. As one of the methods of combating the current COVID-19 pandemic, great hopes are pinned on the widespread use of vaccination. The possibility of using mo noclonal antibodies for pre-exposure prophylaxis of COVID-19, including in patients with IIRD, is discussed.

Publisher

Mediar Press

Subject

Immunology,Immunology and Allergy,Rheumatology

Reference26 articles.

1. Nesterov AI. Rheumatism. Moscow:Meditsina;1973 (In Russ.).

2. Nasonova VA, Bronzov IA. Rheumatism. Moscow:Meditsina;1978 (In Russ.).

3. Dzhuzenova BS, Kotelnikova GP, Mikhaylova IN, Nasonova VA. Acute rheumocarditis in young men. Terapevticheskii arkhiv. 1992;64(4):58-62 (In Russ.).

4. Nasonova VA, Kuzmina NN, Belov BS. Classification and nomenclature of rheumatic fever. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2004;42(2):48-52 (In Russ.).

5. Panasyuk AF, Soldatova SI, Shubin SV, Kolkova NI. On the pathogenetic aspects of urogenic arthritis associated with chlamydia: The possibility of microorganisms to multiply in the cells of articular cartilage. Terapevticheskii arkhiv. 1998;70(5):45-48 (In Russ.).

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3