The use of Anakinra in a patient with a combination of two autoinflammatory diseases: Familial Mediterranean fever and gout-Reference-Cited by-同舟云学术

The use of Anakinra in a patient with a combination of two autoinflammatory diseases: Familial Mediterranean fever and gout

Published:2023-04-28 Issue:2 Volume:61 Page:236-241
ISSN:1995-4492
Container-title:Rheumatology Science and Practice
language:
Short-container-title:Naučno-praktičeskaâ revmatologiâ

Author:

Eliseev M. S.¹^ORCID,Zheliabina O. V.¹^ORCID,Nasonov E. L.²^ORCID,Cheremushkina E. V.¹^ORCID,Korotkova T. A.¹^ORCID,Panevin T. S.¹^ORCID

Affiliation:

1. V.A. Nasonova Research Institute of Rheumatology

2. V.A. Nasonova Research Institute of Rheumatology; I.M. Sechenov First Moscow State Medical University of the Ministry of Health Care of Russian Federation (Sechenov University)

Abstract

Along with familial Mediterranean fever (FMF), it is now considered an autoinflammatory disease and gout. The commonality of the basic mechanisms of inflammation underlying the pathogenesis of FMF and gout predetermines the possibility of using similar therapies aimed at stopping and preventing seizures (colchicine and IL-1 inhibitors). A clinical case is presented describing the presence of a combination of FMF and gout in a patient. The patient was prescribed anakinra, which proved to be effective both as a treatment for FMF and gout. The appointment of an IL-1 inhibitor fully justified expectations: already after the first injection of anakinra, the intensity of swelling and pain in the joints decreased in the patient.

Publisher

Mediar Press

Subject

Immunology,Immunology and Allergy,Rheumatology

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