Comparative Study of Some Physical-Chemical and Immunochemical Properties of Plague Microbe Lipopolysaccharide Preparations Obtained with the Help of Different Techniques-Reference-Cited by-同舟云学术

Comparative Study of Some Physical-Chemical and Immunochemical Properties of Plague Microbe Lipopolysaccharide Preparations Obtained with the Help of Different Techniques

Published:2012-06-20 Issue:3(113) Volume: Page:50-53
ISSN:0370-1069
Container-title:Problems of Particularly Dangerous Infections
language:
Short-container-title:Problemy Osobo Opasnykh Infektsii

Author:

Polunina T. A.¹,Guseva N. P.¹,Kireev M. N.¹,Taranenko T. M.¹,Devdariani Z. L.¹,Zadnova S. P.¹,Kuznetsova E. M.¹,Stepanov A. V.¹,Klyueva S. N.¹,Zakharova T. L.¹

Affiliation:

1. Russian Research Anti-Plague Institute “Microbe”

Abstract

, and degraded polysaccharide (PS) are easily soluble in water and in 0,9 % NaCl solution. They are homogenous and characterized by an adequate degree of purity. Aside from that, it is demonstrated that potentially PS is the most productive molecule fragment of LPS for the construction of plague immunodiagnostic preparation, since despite its decreased cytotoxocity PS retains identity of chemical composition and immunechemical specificity of endotoxin.

Publisher

Russian Research Anti-Plague Institute Microbe

Subject

Infectious Diseases,Microbiology (medical),Immunology,Microbiology,Epidemiology

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