Genesis of Flea-Born Transmission of Plague Microbe, Yersinia pestis: Two Approachs – Molecular-Genetic and Ecological Ones-Reference-Cited by-同舟云学术

Genesis of Flea-Born Transmission of Plague Microbe, Yersinia pestis: Two Approachs – Molecular-Genetic and Ecological Ones

Published:2018-07-04 Issue:2 Volume: Page:37-44
ISSN:0370-1069
Container-title:Problems of Particularly Dangerous Infections
language:
Short-container-title:Problemy Osobo Opasnykh Infektsii

Author:

Suntsov V. V.

Abstract

Two approaches to studying the origin and transmission mechanism of the flea-borne plague pathogen, Yersinia pestis: molecular-genetic and ecological ones – are considered in this review. The molecular genetic approach is based on saltation evolutionary ideology and relies upon the phenomenon of horizontal gene transfer of pla and ymt as critical evolutionary events. Further deletion of some structural and regulatory genes optimized “blockage” mechanism of transmission. The Ecological approach is based on the modern synthetic theory of evolution. It posits a gradual population-genetic transformation in the Marmot – Flea (Marmota sibirica – Oropsylla silantiewi) transitional (heterothermal, heteroimmune) host-parasite system in Late Pleistocene – Holocene epochs. The best prospects for disclosing the mechanisms of evolutionary formation of flea-borne Y. pestis transmission consist in the synthesis of molecular-genetic and ecological approaches.

Publisher

Russian Research Anti-Plague Institute Microbe

Subject

Infectious Diseases,Microbiology (medical),Immunology,Microbiology,Epidemiology

Reference41 articles.

1. Anisimov A.P. [Yersinia pestis factors contributing to cir- culation and preservation of plague agent in eco-systems of natural foci. Communication 1.] Molekulyarnaya Genetika, Mikrobiologiya i Virusologiya. 2002; 3:3–23.

2. Anisimov N.V, Kislichkina A.A., Platonov M.E., Evseeva V.V., Kadnikova L.A., Lipatnikova N.A., Bogun A.G., Dentovskaya S.V., Anisimov A.P. [Concerning the origin of plague agent hypervirulence]. Meditsinskaya Parazitologiya i Parazitarnye Bolezni. 2016; 1:26–32.

3. Kukleva L.M., Boiko A.V. [Plasminogen activator – multi- functional protein of plague pathogen]. Problemy Osobo Opasnykh Infektsii [Problems of Particularly Dangerous Infections]. 2016; 3:13–20. DOI: 10.21055/0370-1069-2016-3-13-20.

4. Kukleva L.M., Protsenko O.A., Kutyrev V.V. [Modern conceptions on the relation between Y. pestis and Yersinia pseudotuberculosis]. Molekulyarnaya Cenetika, Mikrobiologiya i Virusologiya. 2002; 1:3–7.

5. Kutyrev V.V., Eroshenko G.A., Popov N.V., Vidyaeva N.A., Konnov N.P. [Molecular mechanisms of interaction between plague agent and invertebrate animals]. Molekulyarnaya Cenetika, Mikrobiologiya i Virusologiya. 2009; 4:6–13.

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Intraspecific Typing and Phylogeny of the Causative Agent of the Plague—The Microbe Yersinia pestis: Problems and Perspectives;Biology Bulletin Reviews;2024-02

2. Natural foci of plague in Kazakhstan in the space-time continuum;Comparative Immunology, Microbiology and Infectious Diseases;2023-09

3. Prospects for the Synthesis of Ecological and Molecular-Genetic Approaches to the Problem of the Speciation of the Plague Microbe Yersinia pestis;Biology Bulletin Reviews;2020-07