Liver non-contrast perfusion in diffuse liver diseases diagnostic algorithm: the new diagnostic criteria

Abstract

Purpose: to define the new criteria for contrast-free ASL perfusion using for the management of diffuse liver diseases (DLD).Material and methods. Clinical and laboratory data, results of MRI with non-contrast MR perfusion (ASL-perfusion) of the liver  were estimated in a group of patients with DLD (three-year research).Results. Potentials of assessment of liver ASL perfusion for patients with DLD (including complicated cases) are described in the article. It was established that ASL liver perfusion is useful for DLD clinical forms differential diagnosis,  predicting the risk of liver cirrhosis, as well as complications (hepatic encephalopathy, sialoadenitis) and DLD exacerbation. The strategy of contrast-free MR perfusion using  in patients with DLD management algorithm was developed.Conclusion. Liver ASL perfusion is a promising for the study and application method for the management of DLD.