Affiliation:
1. Morozov Children's Clinical Hospital
2. L.A. Vorokhobov City Clinical Hospital (City Hospital No67)
Abstract
Research objective. To study the features of visualization of ischemic stroke in children at the early stages of the formation of the pathological process using magnetic resonance imaging.Material and methods. The results of magnetic resonance imaging (MRI) examination of 34 children with clinical manifestations of ischemic stroke (IS) were analyzed. The analyzed group included patients aged from the 29th day of life to 18 years who had focal changes in the brain substance (BS) during an MRI examination within a period of not more than 48 hours from the onset of neurological symptoms.Results. MRI makes it possible to establish in the early stages of the development of the pathological process the ischemic lesion of the BS in 100% of cases, as well as to evaluate the time indicators of the occurrence of focal changes, based on the analysis and comparison of pulsed MRI sequences, which allow characterizing the severity of the process.Discussion. The analysis of data obtained confirms the results of studies described earlier in the foreign and domestic literature. Moreover, there is a difference in the MR signal specifications from the IS focus during the first 6 hours upon occurrence of the neurological symptoms.Conclusions/findings. The MRI studies in children are important and necessary to determine the IS formation, evaluate the onset and dynamics of the pathological process that contribute to the timely detection of focal changes in the brain structures at the early stages.
Subject
Radiology, Nuclear Medicine and imaging,Radiological and Ultrasound Technology
Reference21 articles.
1. Zykov V.P., Komarova I.B., Ushakova L.V. Diagnosis and treatment of arterial ischemic stroke in children in the acute period. Current Pediatrics = Voprosy Sovremennoi Pediatrii. 2011; 10 (4): 70–77. (In Russian)
2. Koltunov I.E., Melik-Guseinov D.V., Shederkina I.O., Vitkovskaya I.P., Petryaykina E.E. Ischemic stroke in children and adolescents in general pediatric practice. Risk Factors, Early Diagnosis and Primary Prevention. Guidelines No. 127, Moscow, 2019. ISBN 978-5-4465-2327-6
3. Shchederkina I.O., Zavadenko N.N., Koltunov I.E. Stroke in children and adolescents: a formation of a pediatric register. Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova. 2016; 116 (9): 24–29. https://doi.org/10.17116/jnevro20161169124-29 (In Russian)
4. Gelfand A.A., Croen L.A., Torres A.R., Wu Y.W. Genetic risk factors for perinatal arterial ischemic stroke. Pediatr. Neurol. 2013; 48 (1): 36–41. https://doi.org/10.1016/j.pediatrneurol.2012.09.016
5. Zykov V.P., Vasiliev S.A., Komarova I.B. et al. Ischemic stroke in childhood. Lechebnoye delo. 2009; 2: 12–20. (In Russian)