The impact of treatment on endometrium ultrasound findings in reproductive age women with chronic endometritis

Author:

Ozerskaya I. A.1ORCID,Kazaryan G. G.2ORCID,Gus A. I.3ORCID

Affiliation:

1. Peoples' Friendship University of Russia named after Patrice Lumumba; 6, Miklukho-Maklay str., Moscow 117198, Russian Federation

2. LLC “Medskan”; 21A, Obrucheva str., Moscow 119421, Russian Federation

3. Peoples' Friendship University of Russia named after Patrice Lumumba; 6, Miklukho-Maklay str., Moscow 117198, Russian Federation Research Center for Obstetrics, Gynecology and Perinatology named after academician V.I. Kulakov of the Ministry of Healthcare of the Russian Federation; 4, Akademika Oparina str., Moscow 117997, Russian Federation

Abstract

Purpose: to evaluate the dynamics of ultrasound parameter of structural changes of endometrium in B-mode before and after therapy in reproductive age women with chronic endometritis.Material and methods. A retrospective cohort study of 158 reproductive age patients (34.5 ± 6.5 years) with a established diagnosis of chronic endometritis was carried out. Ultrasound was performed twice prior and after comprehensive etiotropic therapy in the proliferative phase of the menstrual cycle with measurements of uterus volume, endometrium thickness and volume, with calculation of endometrial/uterine volume percentage ratio. Echogenicity and structure, including the presence of polyps, liquid in the uterine cavity, gas in   the endometrial layer or on midline, the line of endometrial layers closure and the contour of endometrial midline were assessed.Results. There was no complete regress of any of pathological signs after treatment, but the frequency of most of them decreased significantly (p < 0.05). At the same time, there was no significant changes in such signs as heterogeneous structure and increased echogenicity of the endometrium (p > 0.05). In addition, a statistically significant decrease of endometrium thickness and volume, as well as endometrial/uterine volume ratio was obtained with a constant uterus volume (p < 0.05).Conclusion. The dynamic decrease in the frequency of revealing of the ultrasound signs in chronic endometritis on the background of comprehensive etiotropic therapy allows to assess a positive therapeutic benefits.

Publisher

Vidar, Ltd.

Reference39 articles.

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3. Orazov M.R., Mihaleva L.M., Semenov P.A., Orekhov R.E., Lagutina E.V. The effectiveness of chronic endometritis treatment in women with a history of implantation failures. Difficult patient. 2020; 18 (8–9): 7–12. https://doi.org/10.24411/2074-1995-2020-10053 (In Russian)

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