Abstract
ABSTRACTAs the Vitamin C, Thiamine, and Steroids in Sepsis (VICTAS) Trial was not designed to measure Renin-Angioten-sin-Aldosterone System components, this hub model was developed to limit eight components to a system with one entrance and two exits to facilitate the calculation of angiotensinogen levels. Bootstrapping the bioactive peptide egress rate constant using control subjects and incorporating the previously established renin relationship, the model was used to develop a contingency test to index and classify component relationships.
Publisher
Cold Spring Harbor Laboratory
Reference5 articles.
1. Biochemical evaluation of the renin-angiotensin system: the good, bad, and absolute?
2. Association of Active Renin Content With Mortality in Critically Ill Patients: A Post hoc Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis Trial
3. Westwood BM , Hossam S , Chappell MC . Modeling of Angiotensin Peptide Metabolism in Renal Proximal Tubules. ASME 2008 Summer Bioengineering Conference. 2008 June; SBC2008-190990:181. doi:https://asmedigitalcollection.asme.org/SBC/proceedings-abstract/SBC2008/43215/181/287274.
4. Tukey, John W. : Exploratory Data Analysis. Addison-Wesley Publishing Company Reading, Mass. — Menlo Park, Cal., London, Amsterdam, Don Mills, Ontario, Sydney 1977, XVI, 688 S.
5. The Future of Data Analysis;The Annals of Mathematical Statistics,1962