TIDAL – Tool to Implement Developmental Analysis of Longitudinal data

Author:

Kwong Alex S. F.ORCID,Edmondson-Stait Amelia,Xu Eileen,Thompson Ellen J.,Parker Richard M. A.ORCID,Elhakeem Ahmed,Romaniuk Liana,Pearson Rebecca M.,Tilling Kate,Eley Thalia C.,McIntosh Andrew MORCID,Whalley Heather C.ORCID

Abstract

AbstractMotivationGrowth curve modelling is one method used to model trajectories of traits and behaviours over time. However, accessing, analysing and interpreting trajectories requires statistical expertise, thereby creating potential barriers for users to implement and understand longitudinal traits. TIDAL is a user-friendly research tool designed to facilitate trajectory modelling by improving access, analysis and interpretation of trajectory and longitudinal data.ImplementationTIDAL is available in two formats: an R package and an online Shiny application. The R package can be used offline, negating the need to upload potentially sensitive data.General featuresTIDAL includes all the main steps of trajectory analysis including: 1) data preparation, (converting data from wide to long format); 2) data exploration, via basic plots and descriptive information; 3) analysis of trajectories using mixed effects modelling, interpretation of results, visualisation of trajectories, and extraction of key features (scores at different ages; area under the curve); and 4) interactions to derive population specific trajectories, combined with all the above. TIDAL is built with a simple graphical interface to guide users through each step. R syntax accompanies each step.AvailabilityBoth versions of TIDAL can be found here: [https://tidal-modelling.github.io/].

Publisher

Cold Spring Harbor Laboratory

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