Exploring linkages between drought and HIV treatment adherence in Africa: A Systematic Review

Author:

Orievulu KingsleyORCID,Ayeb-Karlsson SonjaORCID,Ngema Sthembile,Baisley KathyORCID,Tanser FrankORCID,Ngwenya Nothando,Seeley JanetORCID,Hanekom WillemORCID,Herbst KobusORCID,Kniveton Dominic,Iwuji CollinsORCID

Abstract

AbstractClimate change is directly and indirectly linked to human health, including through access to treatment and care. Our systematic review presents a ‘systems’ understanding of the nexus between drought and antiretroviral treatment (ART) adherence in HIV-positive individuals in the African setting. Narrative synthesis of 111 studies retrieved from Web of Science, PubMed/Medline, and PsycINFO suggests that economic and livelihoods conditions, comorbidities and ART regimens, human mobility, and psycho-behavioural dispositions and support systems interact in complex ways in the drought-ART adherence nexus in Africa. Economic and livelihood-related challenges appear to impose the strongest impact on human interactions, actions and systems that culminate in non-adherence. Indeed, the complex pathways identified by our systems approach emphasise the need for more integrated research approaches to understanding this phenomenon and develop interventions.

Publisher

Cold Spring Harbor Laboratory

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