Evaluation of primary allied healthcare in patients recovering from COVID-19: first results after six months follow-up in a Dutch nationwide prospective cohort study

Author:

Slotegraaf Anne I.ORCID,Gerards Marissa H.G.,Verburg Arie C.ORCID,de van der Schueren Marian A.E.ORCID,Kruizenga Hinke M.,Graff Maud J.L.,Cup Edith H.C.,Kalf Johanna G.,Lenssen Antoine F.,Meijer Willemijn M.ORCID,Kool Renée A.,de Bie Rob A.,van der Wees Philip J.,Hoogeboom Thomas J.

Abstract

AbstractObjectivesTo report the recovery of patients receiving primary allied healthcare after a COVID-19 infection at a six-month follow-up, and to explore which patient characteristics are associated with the changes in outcomes between the baseline and six-month follow-up.DesignProspective cohort study.SettingAllied healthcare in Dutch primary care.Participants1,451 adult patients recovering from COVID-19 and receiving treatment from one or more primary care allied health professional(s) (i.e., dietitian, exercise therapist, occupational therapist, physical therapist and/or speech and language therapist).ResultsFor participation (USER-P range 0 to 100), estimated mean differences of at least 2.3 points were observed after six months. For HRQoL (EQ-VAS range 0 to 100), the mean increase was 12.31 at six months. Furthermore, significant improvements were found for fatigue (FSS range 1 to 7): the mean decrease was –0.7 at six months. For physical functioning (PROMIS-PF range 13.8 to 61.3), the mean increase was 5.9 at six months. Mean differences of –0.8 for anxiety (HADS range 0 to 21), and –1.5 for depression (HADS range 0 to 21), were found after six months. Having a worse baseline score, hospital admission and male sex were associated with greater improvement between the baseline and six-month follow-up, whereas age, BMI, comorbidities and smoking status were not associated with mean changes in any outcome measure.ConclusionsPatients recovering from COVID-19 who receive primary allied healthcare make progress in recovery, but still experience many limitations in their daily activities after six months. Our findings provide reference values to healthcare providers and healthcare policy-makers regarding what to expect from the recovery of patients who received health care from one or more primary care allied health professionals.Trial registrationClinicaltrials.govregistry (NCT04735744).

Publisher

Cold Spring Harbor Laboratory

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