A context-dependent switch from sensing to feeling in the primate amygdala

Abstract

SUMMARYThe skin transmits affective signals that integrate into our social vocabulary. As the socio-affective aspects of touch are likely processed in the amygdala, we compared neural responses to social grooming and gentle airflow recorded from the amygdala and the primary somatosensory cortex of non-human primates. Neurons in the somatosensory cortex responded to both types of tactile stimuli. In the amygdala, however, neurons did not respond to individual grooming sweeps even though grooming elicited autonomic states indicative of positive affect. Instead, many showed changes in baseline firing rates that persisted throughout the grooming bout. Such baseline fluctuations were attributed to social context because the presence of the groomer alone could account for the observed changes in baseline activity. It appears, therefore, that during grooming, the amygdala stops responding to external inputs on a short time scale but remains responsive to social context (or the associated affective states) on longer time scales.