Author:
Birney Ewan,Andrews T. Daniel,Bevan Paul,Caccamo Mario,Chen Yuan,Clarke Laura,Coates Guy,Cuff James,Curwen Val,Cutts Tim,Down Thomas,Eyras Eduardo,Fernandez-Suarez Xose M.,Gane Paul,Gibbins Brian,Gilbert James,Hammond Martin,Hotz Hans-Rudolf,Iyer Vivek,Jekosch Kerstin,Kahari Andreas,Kasprzyk Arek,Keefe Damian,Keenan Stephen,Lehvaslaiho Heikki,McVicker Graham,Melsopp Craig,Meidl Patrick,Mongin Emmanuel,Pettett Roger,Potter Simon,Proctor Glenn,Rae Mark,Searle Steve,Slater Guy,Smedley Damian,Smith James,Spooner Will,Stabenau Arne,Stalker James,Storey Roy,Ureta-Vidal Abel,Woodwark K. Cara,Cameron Graham,Durbin Richard,Cox Anthony,Hubbard Tim,Clamp Michele
Abstract
Ensembl (http://www.ensembl.org/) is a bioinformatics project to organize biological information around the sequences of large genomes. It is a comprehensive source of stable automatic annotation of individual genomes, and of the synteny and orthology relationships between them. It is also a framework for integration of any biological data that can be mapped onto features derived from the genomic sequence. Ensembl is available as an interactive Web site, a set of flat files, and as a complete, portable open source software system for handling genomes. All data are provided without restriction, and code is freely available. Ensembl's aims are to continue to “widen” this biological integration to include other model organisms relevant to understanding human biology as they become available; to “deepen” this integration to provide an ever more seamless linkage between equivalent components in different species; and to provide further classification of functional elements in the genome that have been previously elusive.
Publisher
Cold Spring Harbor Laboratory
Subject
Genetics (clinical),Genetics