A Connectome of the MaleDrosophilaVentral Nerve Cord
Author:
Takemura Shin-ya, Hayworth Kenneth JORCID, Huang Gary BORCID, Januszewski MichalORCID, Lu ZhiyuanORCID, Marin Elizabeth CORCID, Preibisch StephanORCID, Xu C ShanORCID, Bogovic JohnORCID, Champion Andrew SORCID, Cheong Han SJORCID, Costa MartaORCID, Eichler KatharinaORCID, Katz WilliamORCID, Knecht ChristopherORCID, Li FengORCID, Morris Billy JORCID, Ordish ChristopherORCID, Rivlin Patricia KORCID, Schlegel PhilippORCID, Shinomiya Kazunori, Stürner TomkeORCID, Zhao TingORCID, Badalamente GriffinORCID, Bailey DennisORCID, Brooks PaulORCID, Canino Brandon SORCID, Clements JodyORCID, Cook MichaelORCID, Duclos OctaveORCID, Dunne Christopher RORCID, Fairbanks KelliORCID, Fang Siqi, Finley-May SamanthaORCID, Francis AudreyORCID, George Reed, Gkantia MarinaORCID, Harrington KyleORCID, Hopkins Gary PatrickORCID, Hsu JosephORCID, Hubbard Philip MORCID, Javier AlexandreORCID, Kainmueller DagmarORCID, Korff WyattORCID, Kovalyak JulieORCID, Krzemiński DominikORCID, Lauchie Shirley AORCID, Lohff AlannaORCID, Maldonado CharliORCID, Manley Emily AORCID, Mooney CarolineORCID, Neace ErikaORCID, Nichols Matthew, Ogundeyi OmotaraORCID, Okeoma NneomaORCID, Paterson TylerORCID, Phillips ElliottORCID, Phillips Emily M, Ribeiro CaitlinORCID, Ryan Sean MORCID, Rymer Jon ThomsonORCID, Scott Anne K, Scott Ashley LORCID, Shepherd DavidORCID, Shinomiya AyaORCID, Smith Claire, Smith NatalieORCID, Suleiman AliaORCID, Takemura SatokoORCID, Talebi IrisORCID, Tamimi Imaan FMORCID, Trautman Eric TORCID, Umayam LowellORCID, Walsh John JORCID, Yang TansyORCID, Rubin Gerald MORCID, Scheffer Louis KORCID, Funke JanORCID, Saalfeld StephanORCID, Hess Harald FORCID, Plaza Stephen MORCID, Card Gwyneth MORCID, Jefferis Gregory SXEORCID, Berg StuartORCID
Abstract
AbstractAnimal behavior is principally expressed through neural control of muscles. Therefore understanding how the brain controls behavior requires mapping neuronal circuits all the way to motor neurons. We have previously established technology to collect large-volume electron microscopy data sets of neural tissue and fully reconstruct the morphology of the neurons and their chemical synaptic connections throughout the volume. Using these tools we generated a dense wiring diagram, or connectome, for a large portion of theDrosophilacentral brain. However, in most animals, including the fly, the majority of motor neurons are located outside the brain in a neural center closer to the body, i.e. the mammalian spinal cord or insect ventral nerve cord (VNC). In this paper, we extend our effort to map full neural circuits for behavior by generating a connectome of the VNC of a male fly.
Publisher
Cold Spring Harbor Laboratory
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