Spatial and temporal clustering of anti-SARS-CoV-2 antibodies in Illinois household cats, 2021-2023

Abstract

ABSTRACTThis study evaluated the seroprevalence of SARS-CoV-2 antibodies in Illinois household cats from October 2021 to May 2023. Among 1,715 samples tested by serological assays, 244 samples (14%) tested positive. High-rate temporal, spatial, and space-time clusters of SARS-CoV-2 cases were assessed within 63 counties in Illinois. Three space-time clusters with higher than expected seroprevalence rates were identified in the northeastern, central-east, and southwest regions of Illinois, occurring between June and October 2022. Young cats had a higher seropositivity than older cats, and the third quarter of the year had the highest odds of seropositivity . This study provides an in-depth analysis of SARS-CoV-2 epidemiology in Illinois household cats, which will aid in COVID-19 control and prevention.Article summary lineSARS-CoV-2 antibody seroprevalence was assessed in Illinois domestic cats, in which a higher seropositivity rate was clustered in the northern, central, and southern Illinois regions with peak periods occurring between June and October 2022.