Author:
Adeyemi Oluwaseun,DiMaggio Charles,Grudzen Corita,Allison Cuthel,Van Allen Kaitlyn,Chodosh Joshua
Abstract
AbstractBackgroundFalls are the leading injury-related cause of death among older adults but rapid emergency care may reduce fatal complications. To estimate the strength of the association between EMS response times and fatal fall injuries among older adults and measure how this association differs by sex.MethodsFor this retrospective cohort study, we pooled 2015 – 2020 data from the National Trauma Data Bank on patients 65 years and older with fall injuries transferred to U.S. trauma centers (N=705,491). The main outcome was fatal fall injuries. The main predictor was EMS response time, measured as continuous and four-level categorical variables (multiples of the standard nine-minute benchmark). Age, sex, race/ethnicity, and diagnoses of COPD, diabetes, and hypertension were covariables. We performed a mixed-effect multivariable logistic regression, using the trauma center designation level as a random effect variable, and EMS response time and mortality as fixed effect variables. We report the unadjusted and adjusted odds ratio (AOR) plus 95% confidence intervals (CI). We also created an interaction model comprising of response time and sex and reported the predicted probabilities (plus 95% CI) of fatal fall injury by sex and response time categories.ResultsThe case fatality rate of fatal fall injuries among adults 65 years and older was 4.4%. The median (Q1, Q3) EMS response time was 8 minutes (5.0, 13.0), with 60% of patients experiencing the nine-minute benchmark. In the adjusted model, a minute delay in EMS response time was associated with a 1% increased odds of fatal fall injury (AOR: 1.01; 95% CI: 1.01 – 1.01). Older adults who experienced a response time between 18 and 27 minutes, and more than 27 minutes had 1.33 (95% CI: 1.28 - 1.39), and 1.41 (95% CI: 1.35 - 1.47) times the odds of fatal fall injuries. The predicted probabilities of male and female fatal fall injuries were 5.1% (95% CI: 3.51 – 6.75) and 2.4% (95% CI: 1.64 – 3.23), respectively.ConclusionDelayed EMS response time, especially when above twice the standard benchmark, is associated with increased odds of fatal fall injuries among older adults.Key PointsQuestionWhat is the association between EMS response time and fatal fall injuries among US older adults?FindingsIn this retrospective cohort analysis, delay in EMS response time was associated with fatal fall injury in a dose-response pattern among male and female older adults.MeaningStrengthening the EMS infrastructure may improve outcomes from fatal fall injuries among older adults.
Publisher
Cold Spring Harbor Laboratory
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