Augmenting propulsion demands during split-belt walking increases locomotor adaptation in the asymmetric motor system

Abstract

AbstractBackgroundPromising studies have shown that the mobility of individuals with hemiparesis due to brain lesions, such as stroke, can improve through motor adaptation protocols forcing patients to use their affected limb more. However, little is known about how to facilitate this process. Here we asked if increasing propulsion demands during split-belt walking (i.e., legs moving at different speeds) leads to more motor adaptation and more symmetric gait in survivors of a stroke, as we previously observed in subjects without neurological disorders.MethodsWe investigated the effect of propulsion forces on locomotor adaptation during and after split-belt walking in the asymmetric motor system post-stroke. To test this, 12 subjects in the chronic phase post-stroke experienced a split-belt protocol in a flat and incline session so as to contrast the effects of two different propulsion demands. Step length asymmetry and propulsion forces were used to compare the motor behavior between the two sessions because these are clinically relevant measures that are altered by split-belt walking.ResultsThe incline session resulted in more symmetric step lengths during late split-belt walking and larger after-effects following split-belt walking. In both testing sessions, subjects who have had a stroke adapted to regain speed and slope-specific leg orientations similarly to young, intact adults. Importantly, leg orientations during baseline walking were predictive of those achieved during split-belt walking, which in turn predicted each individual’s post-adaptation behavior.ConclusionThese results indicated that survivors of a stroke can adapt their movements to meet leg-specific kinetic demands. This promising finding suggests that augmenting propulsion demands during split-belt walking could favor symmetric walking in individuals who had a stroke, possibly making split-belt interventions a more effective gait rehabilitation strategy.