ZGA: a flexible pipeline for read processing, de novo assembly and annotation of prokaryotic genomes

Abstract

AbstractMotivationWhole genome sequencing (WGS) became a routine method in modern days and may be applied to study a wide spectrum of scientific problems. Despite increasing availability of genome sequencing by itself, genome assembly and annotation could be a challenge for an inexperienced researcher.ResultsZGA is a computational pipeline to assemble and annotate prokaryotic genomes. The pipeline supports several modern sequencing platforms and may be used for hybrid genome assembling. Resulting genome assembly is ready for deposition to an INSDC database or for further analysis.AvailabilityZGA was written in Python, the source code is freely available at https://github.com/laxeye/zga/. ZGA can be installed via Anaconda Cloud and Python Package Index.Contactoscypek@ya.ruSupplementary informationSupplementary data are available at Bioinformatics online.