Fast Assembling of Neuron Fragments in Serial 3D Sections

Author:

Chen HanboORCID,Iascone Daniel M.,da Costa Nuno Macarico,Lein Ed S.,Liu Tianming,Peng Hanchuan

Abstract

Abstract:Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3D image sections. With its efficient algorithm and user-friendly interface, NeuronStitcher has been used successfully to reconstruct very large and complex human and mouse neurons.

Publisher

Cold Spring Harbor Laboratory

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