On Post-Acquisition Motion Compensation for Prostate Perfusion Analysis

Author:

Wollny Gert,Casanova Isabel,Ledesma-Carbayo Maria-Jesus,Santos Andres

Abstract

Dynamic Contrast enhance magnetic resonance imaging has been established as an accurate method to detect and localize prostate cancer. Time series of three-dimensional datasets of the prostate are acquired and used to obtain per-voxel signal-intensity vs. time curves. These are then used to differentiate cancerous from non-cancerous tissue. However, rectal peristalsis and patient movement may result in spatial-mismatching of the serial datasets and therefore, incorrect enhancement curves. In this work, we discuss and test four methods based on image registration to compensate for these movements. These methods include a serial approach that uses the registration of consecutive images and the accumulation of the obtained transformations, an all-to one registration approach, an approach that first aligns a sub-set of images that are already closely aligned, and then uses synthetic references to register the remaining images, and an approach that uses independent component analysis (ICA) to create synthetic references and register the images to these. We conclude that the method based on ICA does not provide a viable approach for motion compensation in prostate perfusion imaging, and that the serial approach fails when motion artifacts are present in the series. The other two approaches provide qualitatively pleasing results.

Publisher

Cold Spring Harbor Laboratory

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3