Dysfunctional temporal stages of eye-gaze perception in adults with ADHD: a high-density EEG study-Reference-Cited by-同舟云学术

Dysfunctional temporal stages of eye-gaze perception in adults with ADHD: a high-density EEG study

Published:2021-10-16 Issue: Volume: Page:
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Author:

Mauriello Cheyenne,Pham Eleonore,Kumar Samika,Piguet Camille,Deiber Marie-Pierre,Aubry Jean-Michel,Dayer Alexandre,Michel Christoph M.,Perroud Nader,Berchio Cristina

Abstract

AbstractADHD have been associated with social cognitive impairments across the lifespan, but no studies have specifically addressed the presence of abnormalities in eye-gaze processing in the adult brain.This study investigated the neural basis of eye-gaze perception in adults with ADHD using event-related potentials (ERP). Twenty-three ADHD and 23 controls performed a delayed face-matching task with neutral faces that had either direct or averted gaze. ERPs were classified using microstate analyses.ADHD and controls displayed similar P100 and N170 microstates. ADHD was associated with cluster abnormalities in the attention-sensitive P200 to direct gaze, and in the N250 related to facial recognition. For direct gaze, source localization revealed reduced activity in ADHD for the P200 in the left/midline cerebellum, as well as in a cingulate-occipital network at the N250. These results suggest brain impairments involving eye-gaze decoding in adults with ADHD, suggesting that neural deficits persist across the lifespan.

Publisher

Cold Spring Harbor Laboratory

Reference83 articles.

1. Neural correlates of impaired emotional face recognition in cerebellar lesions;Brain research,2015

2. Effects of Direct and Averted Gaze on the Perception of Facially Communicated Emotion.

3. Facial emotion recognition and eye gaze in attention-deficit/hyperactivity disorder with and without comorbid conduct disorder;Journal of the American Academy of Child Adolescent Psychiatry,2018

4. APA. (2013). Diagnostic and statistical manual of mental disorders (DSM-5®): American Psychiatric Pub.

5. Baradits, M. , Bitter, I. , & Czobor, P. J. P. r. (2020). Multivariate patterns of EEG microstate parameters and their role in the discrimination of patients with schizophrenia from healthy controls. 288(112938).