Abstract
AbstractThe aim of this study was to evaluate the performance of blood screening strategies in Nagqu City, with a focus on serological and nucleic acid testing effectiveness. Analysis of blood donation data from 2017 to 2023 revealed a gradual increase in local blood donation rates, but the rate of unqualified donations remained higher than the national average. Serological performance verification showed good repeatability and precision, but improvements are needed in the accuracy of certain markers. Nucleic acid performance verification demonstrated excellent detection capability for low viral load HBV infections. The conclusion highlights significant progress in the screening strategies of Nagqu City, with the nucleic acid testing system showing outstanding performance. The findings provide valuable insights for blood screening in other high-altitude regions.
Publisher
Cold Spring Harbor Laboratory