Genetic variability in the promoter region of TNF-α gene in the reservoir of Junin virus, Calomys musculinus (Rodentia, Cricetidae)-Reference-Cited by-同舟云学术

Genetic variability in the promoter region of TNF-α gene in the reservoir of Junin virus, Calomys musculinus (Rodentia, Cricetidae)

Published:2017-03-04 Issue: Volume: Page:
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Author:

Chiappero Marina B.,Cabaña Imanol,Calderón Gladys E.,Gardenal Cristina N.

Abstract

AbstractIn this study, we assessed the genetic variability of the promoter region of TNF-α gene in three natural populations of the cricetid rodent Calomys musculinus. This species is the natural reservoir of Junin virus, the etiological agent of Argentine Hemorrhagic fever. We found different levels of variability and varying signatures of natural selection in populations with different epidemiological histories.

Publisher

Cold Spring Harbor Laboratory

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