Ancient DNA supports that the evolution of Skin Tone in East Asians intensified after their split with Native Americans

Author:

Ferrando-Bernal Manuel

Abstract

AbstractSkin tone has been deeply studied in European populations both using modern and ancient DNA. However, other populations are underrepresented in such studies. One such population is East Asians, for which, interestingly, it has been claimed to evolve light skin tones in parallel to Europeans. Moreover, it is not clear whether this happened before or after their split from Native Americans. Over the last few years, several studies have sequenced hundreds of ancient genomes belonging to East Asians ancient populations. Additionally, some variants have been associated with light skin in East Asians. To shed some light, I applied a Polygenic Risk Score for some of the variants associated with light skin, in 237 modern Native Americans and East Asian individuals and in more than 700 East Asians ancient samples. The results suggest that this phenotype may have started to evolve in the ancestors of East Asians and Native Americans but intensified after their split.

Publisher

Cold Spring Harbor Laboratory

Reference25 articles.

1. The evolution of skin pigmentation-associated variation in West Eurasia

2. Human skin pigmentation as an adaptation to UV radiation;PNAS,2010

3. Adaptation of human skin color in various populations

4. Neale Lab . UK Biobank GWAS. http://www.nealelab.is/uk-biobank.

5. A High-Coverage Genome Sequence from an Archaic Denisovan Individual;Science,2012

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3