Estimating VO2peak in 18-91 year-old adults: Development and Validation of the FitMáx© - Questionnaire

Author:

Meijer RenskeORCID,Hooff Martijn vanORCID,Papen-Botterhuis Nicole E.ORCID,Molenaar Charlotte J.L.ORCID,Regis MartaORCID,Timmers ThomasORCID,van de Poll-Franse Lonneke V.ORCID,Savelberg Hans H.C.M.ORCID,Schep GoofORCID

Abstract

AbstractObjectivesCardiorespiratory fitness plays an essential role in health outcomes and quality of life. Objective assessment of cardiorespiratory fitness is costly, labour intensive and not widely available. Although patient-reported outcome measures estimate cardiorespiratory fitness more cost-efficiently, the current questionnaires lack accuracy. The aim of this study is to develop and validate the FitMáx©-questionnaire, a self-reported questionnaire to estimate cardiorespiratory fitness in healthcare.MethodsWe developed the FitMáx©-questionnaire, consisting of three questions assessing walking, stair climbing, and cycling capacity. A comparison on estimating VO2peak was made with the Duke Activity Status Index (DASI), Veterans Specific Activity Questionnaire (VSAQ) and cardiopulmonary exercise testing as the gold standard. A total of 716 patients and athletes (520 men, 196 women) aged 18□91 performed a CPET in our hospital. We randomly selected 70% of the subjects to fit a linear regression model to estimate VO2peak based on the FitMáx© scores. The remaining 30% of participants was used for validation of this model.ResultsThe VO2peak estimated by the FitMáx© strongly correlates with the VO2peak measured objectively with CPET; r=0.95 (0.93□0.96) SEE=3.94 ml·kg-1·min-1. Bias between predicted and measured VO2peak was 0.32 ml·kg-1·min-1 and the 95% limits of agreement were −8.11 □ 9.40 ml·kg-1·min-1. In our sample, the FitMáx scored superiorly on correlation and SEE compared with those from the DASI and VSAQ, r=0.80 (0.73□0.86) SEE=4.22 ml·kg-1·min-1 and r=0.88 (0.84□0.91) SEE=6.61 ml·kg-1·min-1, respectively.ConclusionFitMáx© is a valid and accessible questionnaire to estimate cardiorespiratory fitness expressed as VO2peak and shows substantial improvement compared to currently used questionnaires.Key pointsFitMáx© relies on three simple single-answer questions, which are recognizable for a large population, to accurately estimate cardiorespiratory fitness.The FitMáx© is a self-reported instrument in which involvement of physicians, healthcare providers or other instrumentation is not necessary.Cardiorespiratory fitness estimated by the FitMáx© may serve as an easily applicable measure in clinical and non-clinical settings.

Publisher

Cold Spring Harbor Laboratory

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