A human monoclonal antibody blocking SARS-CoV-2 infection

Author:

Wang Chunyan,Li Wentao,Drabek Dubravka,Okba Nisreen M.A.,van Haperen Rien,Osterhaus Albert D.M.E.,van Kuppeveld Frank J.M.,Haagmans Bart L.,Grosveld Frank,Bosch Berend-Jan

Abstract

AbstractThe emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV). This cross-neutralizing antibody targets a communal epitope on these viruses and offers potential for prevention and treatment of COVID-19.

Publisher

Cold Spring Harbor Laboratory

Reference24 articles.

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