PANDA: A comprehensive and flexible tool for proteomics data quantitative analysis

Author:

Chang ChengORCID,Guo Chaoping,Ding Yuqing,Xu Kaikun,Han Mingfei,He Fuchu,Zhu Yunping

Abstract

ABSTRACTSummaryAs the experiment techniques and strategies in quantitative proteomics are improving rapidly, the corresponding algorithms and tools for protein quantification with high accuracy and precision are continuously required to be proposed. Here, we present a comprehensive and flexible tool named PANDA for proteomics data quantification. PANDA, which supports both label-free and labeled quantifications, is compatible with existing peptide identification tools and pipelines with considerable flexibility. Compared with MaxQuant on two complex da-tasets, PANDA was proved to be more accurate and precise with less computation time. Additionally, PANDA is an easy-to-use desktop ap-plication tool with user-friendly interfaces.AvailabilityPANDA is freely available for download at https://sourceforge.net/projects/panda-tools/.Contact1987ccpacer@163.com and zhuyunping@gmail.com

Publisher

Cold Spring Harbor Laboratory

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