Abstract
AbstractIn the United States, typhoid vaccination is recommended for international travelers to areas with a recognized risk of typhoid exposure. Using MarketScan® Commercial Database from 2016 through 2022, we estimated typhoid vaccination costs by route (injectable vs. oral) and provider setting (clinic vs. pharmacy). Of 165,930 vaccinated individuals, 99,471 received injectable and 66,459 received oral typhoid vaccines, with 88% and 17% respectively administered at clinics. Average costs for injectable vaccination were $132.91 per person [95% confidence interval (CI): $132.68–$133.13], with clinic and pharmacy costs at $136.38 [95% CI: $136.14–$136.63], and $107.45 [95% CI: $107.13–$107.77] respectively. Oral vaccination costs averaged $81.23 per person [95% CI: $81.14–$81.33], encompassing $86.61 [95% CI: $86.13– $87.10] at clinics and $80.14 [95% CI: $80.09–$80.19] at pharmacies. Out-of-pocket costs comprised 21% and 33% of total costs for injectable and oral vaccinations. These findings may inform clinical decision-making to protect international travelers’ health.
Publisher
Cold Spring Harbor Laboratory
Reference17 articles.
1. Typhoid Fever Surveillance, Incidence Estimates, and Progress Toward Typhoid Conjugate Vaccine Introduction — Worldwide, 2018–2022
2. Institute for Health Metrics and Evaluation. Typhoid fever-level 4 cause. Seattle, WA: Institute for Health Metrics and Evaluation, Global Burden of Disease Collaborative Network; 2020.
3. Centers for Disease Control and Prevention (CDC). National Typhoid and Paratyphoid Fever Surveillance Annual Report, 2020. 2023.
4. Typhoid Fever in the United States, 1999-2006
5. Vaccination against typhoid fever in travellers: a cost-effectiveness approach