Trends in syphilis prevalence by race and ethnicity among people who are pregnant in the United States 2014–2022

Author:

Liang YizhiORCID,Menzies Nicolas AORCID,Rönn Minttu MORCID

Abstract

AbstractThis study aimed to estimate syphilis prevalence among people who are pregnant with live births by race and ethnicity 2014–2022. We analyzed data on syphilis infection from birth certificates using a Bayesian model, adjusting for test sensitivity, specificity, and screening coverage. We estimated syphilis prevalence among people who are pregnant with live births increased from 88.7 (95% UI: 77.3–104.7) per 100,000 live births in 2014 to 462.2 (95% UI: 430.9–502.4) per 100,000 live births in 2022. With rising prevalence, relative racial and ethnic disparities narrowed over time. Syphilis prevalence is likely higher among women with stillbirths, indicating a need for improved screening and interventions.One sentence summary lineWe estimated an increasing syphilis prevalence among people who are pregnant, reaching 462 per 100,000 live births in 2022, and notable racial and ethnic disparities in prevalence.

Publisher

Cold Spring Harbor Laboratory

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