Abstract
ABSTRACTThe morbidity, mortality, and diminished quality of life of patients are all impacted by drug-related problems. Stroke is one of the leading causes of disability and death in India and since the stroke patients are at an increased risk of DRPs (Drug Related Problems), early identification, prevention and resolution of the same is important for improving the quality of life of stroke patients. The aim of the study was to assess the incidence of DRPs in stroke patients by using Hepler-strand classification and the acceptance rate by the multidisciplinary team. The relevant information were documented using a predefined data collection form and was analyzed for drug related problems and categorized according to Hepler–Strand classification. A total of 510 DRPs from 130 participants with an average incidence of 3.92 DRPs per patient. Drug-drug interaction was found to be 23.53% and ADRs accounted for 12.55 % of total DRPs. The study found a high acceptance rate of recommendations by healthcare professionals at 97.36%, with changes in therapy being made 68.13% of the time. Early detection and resolution of DRP by clinical pharmacist may improve the therapeutic outcomes in stroke patients. This also helps in preventing complications and unnecessary hospitalization, high cost of treatment and deaths among stroke patients.
Publisher
Cold Spring Harbor Laboratory
Reference19 articles.
1. Cerebrovascular disease in the community: results of a WHO collaborative study;Bull World Health Organ,1980
2. World stroke day 2022, World Health Organization. Available at: https://www.who.int/srilanka/news/detail/29-10-2022-world-stroke-day-2022 (Accessed: 01 January 2023).
3. Cardiovascular Disease and Risk Factors in Asia
4. Low cholesterol as a risk factor for primary intracerebral hemorrhage: A case-control study
5. DiPiro JT , Yee GC , Posey LM , Haines ST , Nolin TD , Ellingrod VL . Pharmacotherapy: A pathophysiologic approach. 12th ed. New York: McGraw Hill; 2020.